Publications

IL-7/IL-15/IL-21 Cytokine-Fusion Scaffold Generates Highly Functional CAR-T Cells Enriched in Long-lived T Memory Stem Cells

Science Advances, Cole E…Wong H., Goldstein H. et al., March 13 th , 2026

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TGF-βRII/IL-15 Immunotherapeutic Complex Targets Exhausted CD8+ T-Cell Subsets in Lymph Nodes and Tumors

Journal for ImmunoTherapy of Cancer, George VK, Wong HC et al., December 2025

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A "Prime and Expand" Strategy Using the Multifunctional Fusion Proteins to Generate Memory-Like NK Cells for Cell Therapy

Cancer Immunology, Immunotherapy, Shrestha N. et al., July 3rd , 2024

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Immunotherapeutic Approach to Reduce Senescent Cells and Alleviate Senescence-Associated Secretory Phenotype in Mice

Aging Cell, Shrestha N. et al., March 26th, 2023

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A Novel Interleukin-2-Based Fusion Molecule, HCW9302, Differentially Promotes Regulatory T Cell Expansion to Treat Atherosclerosis in Mice

Frontiers in Immunology, Zhu X. et al., January 25th, 2023

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Immunotherapeutic HCW9218 Augments Anti-tumor Activity of Chemotherapy via NK Cell Mediated Reduction of Therapy Induced Senescent Cells

Molecular Therapy, Chaturvedi P. et al., January 17th, 2022

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Bifunctional TGF-β trap/IL-15 Protein Complex Elicits Potent NK Cell and CD8+ T Cell Immunity Against Solid Tumors

Molecular Therapy, Liu B. et al., October 6th, 2021

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A Fusion Protein Complex that Combines IL12, IL15, and IL18 Signaling to Induce Memory-like NK Cells for Cancer Immunotherapy

Cancer Immunol Res, Becker-Hapak M. et al., September 9th, 2021

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