Publications

Development of Analytical Methods for Detection of Anti-Drug Antibodies Neutralizing IL-15 and TGF-β RII Activity

Journal of Immunoassay and Immunochemistry, Leclerc GM. et al., August 7th, 2025

  • Publications

Enhancing HIV-1-Specific CAR-T Cell Functional Activity by Treatment with a Novel Cytokine-Based Scaffold with IL-15 Superagonist and TGF-β-Neutralizing Activity

Journal of Virology, Lamcaj S…Wong HC, Goldstein H, et al., August 14th, 2026

  • Publications

IL-7/IL-15/IL-21 Cytokine-Fusion Scaffold Generates Highly Functional CAR-T Cells Enriched in Long-lived T Memory Stem Cells

Science Advances, Cole E…Wong H., Goldstein H. et al., March 13 th , 2026

  • Publications

TGF-βRII/IL-15 Immunotherapeutic Complex Targets Exhausted CD8+ T-Cell Subsets in Lymph Nodes and Tumors

Journal for ImmunoTherapy of Cancer, George VK, Wong HC et al., December 2025

  • Publications

A "Prime and Expand" Strategy Using the Multifunctional Fusion Proteins to Generate Memory-Like NK Cells for Cell Therapy

Cancer Immunology, Immunotherapy, Shrestha N. et al., July 3rd , 2024

  • Publications

Immunotherapeutic Approach to Reduce Senescent Cells and Alleviate Senescence-Associated Secretory Phenotype in Mice

Aging Cell, Shrestha N. et al., March 26th, 2023

  • Publications

A Novel Interleukin-2-Based Fusion Molecule, HCW9302, Differentially Promotes Regulatory T Cell Expansion to Treat Atherosclerosis in Mice

Frontiers in Immunology, Zhu X. et al., January 25th, 2023

  • Publications

Immunotherapeutic HCW9218 Augments Anti-tumor Activity of Chemotherapy via NK Cell Mediated Reduction of Therapy Induced Senescent Cells

Molecular Therapy, Chaturvedi P. et al., January 17th, 2022

  • Publications

Bifunctional TGF-β trap/IL-15 Protein Complex Elicits Potent NK Cell and CD8+ T Cell Immunity Against Solid Tumors

Molecular Therapy, Liu B. et al., October 6th, 2021

  • Publications

A Fusion Protein Complex that Combines IL12, IL15, and IL18 Signaling to Induce Memory-like NK Cells for Cancer Immunotherapy

Cancer Immunol Res, Becker-Hapak M. et al., September 9th, 2021

  • Publications